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Proshkina E, Plyusnin S, Babak T, Lashmanova E, Maganova F, Koval L, et al

Not every patient is an appropriate candidate, and a responsible clinician will always screen before recommending treatment

Moreover, following 13 C-glucose tracing in activated Gclc fl/fl and Gclc fl/fl Mb1-Cre + FoB, we detected an increased contribution of glycolytic carbon to lactate within the mutant cells (Fig

This confirmed the efficient Cre -mediated deletion of the Gclc and also suggested that steady state B cells do not import GSH from the environment

cerevisiae mutant library was constructed using UV-induced random mutagenesis to isolate strains with enhanced glutathione production